The Effects of NVX-108 as a Radiation Sensitizer in Glioblastoma

Summary

This clinical trial is testing the safety, tolerability and effectiveness of NVX-108 administered via intravenous infusion in combination with standard radiation and chemotherapy. NVX-108 is being developed to increase the amount of oxygen delivered to tumors which is hoped to increase the effectiveness of radiation therapy.

Timeline

Start

2014-05

Primary completion

2017-08-31

Completion

2018-04

Publications

• Lickliter JD, Ruben J, Kichenadasse G, Jennens R, Gzell C, Mason RP, Zhou H, Becker J, Unger E, Stea B. Dodecafluoropentane Emulsion as a Radiosensitizer in Glioblastoma Multiforme. Cancer Res Commun. 2023 Aug 21;3(8):1607-1614. doi: 10.1158/2767-9764.CRC-22-0433. eCollection 2023 Aug.

Drugs

Indications