drugset / Trial / NCT02192398
Effect of Guanfacine on the Reversal of Opioid-induced Hyperalgesia (OIH)
Terminated
8 enrolled
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Combination of guanfacine with opioid medication as a standard treatment for chronic pain.
Timeline
- Start
- 2014-09
- Primary completion
- 2022-10
- Completion
- 2022-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Guanfacine | Small molecule | 1 mg | — |
| Comparator | Guanfacine | Small molecule | 2 mg | — |