The Effects of Minocycline in Humans

Summary

To determine minocycline's effects on cognitive performance and measures of mood in abstinent cocaine users. Minocycline is a tetracycline derivative antibiotic that also inhibits microglia activation and the release of pro-inflammatory cytokines, chemokines, and nitric oxide (NO) production. Previous animal and human studies suggest that minocycline may have utility as a treatment for cocaine addiction.

Timeline

Start

2013-07-08

Primary completion

2015-11-05

Completion

2015-11-05

Drugs

Indications