drugset / Trial / NCT02194075

Methylphenidate Hydrochloride Controlled-Release Tablets Augmentation Strategy for Patients With Obsessive Compulsive Disorder

NCT02194075

Phase 4 Completed 60 enrolled Guangdong Provincial People's Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

Explore the efficacy of methylphenidate hydrochloride controlled-release tablets add-on pharmacotherapy on clinical symptomatology and cognitive functioning in a sample of patients with obsessive-compulsive disorder (OCD) receiving fluvoxamine maleate. To test the hypothesis that methylphenidate hydrochloride controlled-release tablets augmentation of fluvoxamine treatment is well tolerated and may be proposed as an effective therapeutic strategy to improve outcome in OCD.

Timeline

Start
2013-10
Primary completion
2015-10
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Methylphenidate Small molecule 18 mg
Comparator Methylphenidate Small molecule 36 mg
Comparator Fluvoxamine Unknown 100 mg
Comparator Fluvoxamine Unknown 300 mg