drugset / Trial / NCT02194075
Methylphenidate Hydrochloride Controlled-Release Tablets Augmentation Strategy for Patients With Obsessive Compulsive Disorder
RandomizedParallel-groupTriple-blindTreatment
Summary
Explore the efficacy of methylphenidate hydrochloride controlled-release tablets add-on pharmacotherapy on clinical symptomatology and cognitive functioning in a sample of patients with obsessive-compulsive disorder (OCD) receiving fluvoxamine maleate. To test the hypothesis that methylphenidate hydrochloride controlled-release tablets augmentation of fluvoxamine treatment is well tolerated and may be proposed as an effective therapeutic strategy to improve outcome in OCD.
Timeline
- Start
- 2013-10
- Primary completion
- 2015-10
- Completion
- 2015-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Methylphenidate | Small molecule | 18 mg | — |
| Comparator | Methylphenidate | Small molecule | 36 mg | — |
| Comparator | Fluvoxamine | Unknown | 100 mg | — |
| Comparator | Fluvoxamine | Unknown | 300 mg | — |