drugset / Trial / NCT02197143

A Comparison of Efficacy of Intravenous Esomeprazole and Ranitidine Treatment of Dyspeptic Pain

NCT02197143

Phase 4 Completed 286 enrolled Pamukkale University
RandomizedFactorialTriple-blindTreatment

Summary

* Currently, Proton Pump Inhibitors and H2Receptor Blockers are widely used by emergency physicians in Turkey for the treatment of patients with dyspepsia. * The objective of the study was to assess whether intravenous esomeprazol has superior dyspeptic pain reduction compared with ranitidine or hydrotalcid in emergency department (ED) adults * The investigators second aim was to compare recurrent dyspeptic pain within 24 hours after discharge and cost of treatments in the treatment of dyspepsia.

Timeline

Start
2013-03
Primary completion
2014-07
Completion
2014-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Esomeprazole Small molecule 40 mg Intravenous
Subject Ranitidine Unknown 50 mg Intravenous
Background hydrotalcid Unknown 10 ml Oral

Indications