drugset / Trial / NCT02197884
A Study to Assess Effects of Clarithromycin on Pharmacokinetics of JNJ-54861911 in Healthy Male Participants
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the effects of strong cytochrome P450 (CYP) 3A4 inhibitors (Itraconazole and Clarithromycin), on pharmacokinetics (PK) (study of the way a drug enters and leaves the blood and tissues over time) of single dose of JNJ-54861911 in healthy male participants.
Timeline
- Start
- 2014-07
- Primary completion
- 2014-09
- Completion
- 2014-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atabecestat | Small molecule | 25 mg | Oral |
| Subject | Clarithromycin | Small molecule | 500 mg | Oral |
| Subject | Itraconazole | Small molecule | 200 mg | Oral |
Indications
No indication recorded.