Randomized Controlled Trial of Treatment of Male Partners of Women With BV

NCT02209519 ↗

Phase 3 Completed 214 enrolled University of Alabama at Birmingham Wayne State University · collab

RandomizedSingle-groupQuadruple-blindPrevention

Summary

Male partners of womoen with recurrent bacteria vaginosis are randomized to treatment with metronidazole or placebo to compare the rates of recurrent BV in the women

Timeline

Start: 2015-02
Primary completion: 2019-03
Completion: 2019-03

Outcome

Missed primary endpoint

paper there was no significant difference between treatment arms for the primary outcome. PMID 33383580 ↗

Publications

Schwebke JR, Lensing SY, Lee J, Muzny CA, Pontius A, Woznicki N, Aguin T, Sobel JD. Treatment of Male Sexual Partners of Women With Bacterial Vaginosis: A Randomized, Double-Blind, Placebo-Controlled Trial. Clin Infect Dis. 2021 Aug 2;73(3):e672-e679. doi: 10.1093/cid/ciaa1903.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Metronidazole	Small molecule	500 mg	Oral