Clinical Study of Generic and Brand Bupropion in Depression

Summary

Determine bioequivalence between branded and generic bupropion extended release (XL) products (and between generic products) at steady state in patients with major depressive disorder.

Timeline

Start

2014-06-25

Primary completion

2016-08-14

Completion

2016-08-14

Publications

• Kharasch ED, Lenze EJ. Pharmacogenetic Influence on Stereoselective Steady-State Disposition of Bupropion. Drug Metab Dispos. 2024 Apr 16;52(5):455-466. doi: 10.1124/dmd.124.001697.

Drugs

Indications