drugset / Trial / NCT02209987

Absolute Bioavailability, Safety, and Tolerability of Subcutaneous GS-5745 in Healthy Adults

NCT02209987

Phase 1 Completed 28 enrolled Gilead Sciences
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will estimate the absolute bioavailability of subcutaneously injected GS-5745, characterize the safety, tolerability, and pharmacokinetics (PK) of GS-5745 after subcutaneous (SC) injection and intravenous (IV) administration, and evaluate the formation of anti-GS-5745 antibodies after SC and IV administration.

Timeline

Start
2014-08
Primary completion
2014-10
Completion
2014-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Andecaliximab Monoclonal antibody 150 mg Subcutaneous

Indications