drugset / Trial / NCT02215629

Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia

NCT02215629 ↗

Phase 1 Withdrawn Verastem, Inc.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The main purpose of this study is to test the safety and efficacy of VS-4718 in two types of leukemia patients and to find the right dose of VS-4718 for future clinical trials. Other purposes of this study include: * Testing for study drug VS-4718 levels in blood over time and what happens to the study drug in patients. * To find out if there are certain biomarkers in leukemia patients that predict if and how 4718 study drug may or may not work.

Timeline

Start
—
Primary completion
2016-09
Completion
2016-11

Drugs

EvaluationDrugModalityDoseRoute
Subject VS-4718 Small molecule — Oral