drugset / Trial / NCT02217852
Treatment of Hypertension in Tibetan Adult Population
RandomizedParallel-groupOpen-labelTreatment
Summary
Several surveys had revealed that Tibetan adults had high prevalence of hypertension. However, there was no research studying the antihypertensive effect of the known drugs in Tibetan. The main arms of our study were to determine if the efficacy of lowing blood pressure and protecting target organ damage differs between nitrendipine and Hydrochlorothiazide in mild hypertension in Tibetan, and to determine if the efficacy of lowing blood pressure and protecting target organ damage differs between captopril plus Hydrochlorothiazide and Beijing hypotensive No.0 in moderate and severe Tibetan hypertension.
Timeline
- Start
- 2014-08
- Primary completion
- 2016-01
- Completion
- 2016-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Beijing hypotensive No.0 | Unknown | — | Oral |
| Subject | Captopril | Small molecule | 25 mg | Oral |
| Subject | Captopril | Small molecule | 50 mg | Oral |
| Subject | Hydrochlorothiazide | Unknown | 12.5 mg | Oral |
| Subject | Hydrochlorothiazide | Unknown | 25 mg | Oral |
| Subject | Nitrendipine | Small molecule | 10 mg | Oral |
| Subject | Nitrendipine | Small molecule | 20 mg | Oral |