drugset / Trial / NCT02224521
GSK2190915A - Bioavailability Study
RandomizedCrossoverOpen-labelOther
Summary
GSK2190915 is a high affinity 5-lipoxygenase-activating protein (FLAP) inhibitor that reduces inflammation in cells. This study will evaluate three capsule and two tablet formulations to select the optimal formulation for further development. Safety will be assessed through clinical laboratory testing, 12-lead electrocardiogram (ECG), vital signs and Adverse Event/ Serious Adverse Event (AE/ SAE) recording.
Timeline
- Start
- 2009-04-20
- Primary completion
- 2010-06-08
- Completion
- 2010-06-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | FIBOFLAPON | Small molecule | 20 mg | — |
| Subject | FIBOFLAPON | Small molecule | 50 mg | — |
| Subject | FIBOFLAPON | Small molecule | 100 mg | — |
| Subject | FIBOFLAPON | Small molecule | 200 mg | — |