drugset / Trial / NCT02229773

Pharmacodynamics, Preliminary Pharmacokinetics and Tolerability of BIBB 1464 (Tablet) in Hyperlipemic Healthy Male Subjects

NCT02229773

Phase 1 Completed 100 enrolled Boehringer Ingelheim
RandomizedParallel-groupDouble-blindTreatment

Summary

Lipid lowering effect, investigation of pharmacodynamics (inhibition of oxidosqualene cyclase, monoepoxysqualene (MES) as marker), safety / tolerability and preliminary pharmacokinetics

Timeline

Start
2000-01
Primary completion
2000-05
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject BIBB 1464 Unknown 0.25 mg Oral
Subject BIBB 1464 Unknown 0.5 mg Oral
Subject BIBB 1464 Unknown 1 mg Oral
Comparator Pravastatin Small molecule 20 mg Oral

Indications

No indication recorded.