drugset / Trial / NCT02230878
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42847922 in Healthy Participants
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to investigate the safety, tolerability, pharmacokinetic (the study of the way a drug enters and leaves the blood and tissues over time), dose-proportionality, accumulation, urinary excretion, pharmacodynamics (the study of how drugs act on the body) and sedative effects of JNJ-42847922 in healthy male and female participants.
Timeline
- Start
- 2014-05
- Primary completion
- 2014-11
- Completion
- 2014-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Seltorexant | Small molecule | 5 mg | — |
| Subject | Seltorexant | Small molecule | 10 mg | — |
| Subject | Seltorexant | Small molecule | 20 mg | — |
| Subject | Seltorexant | Small molecule | 40 mg | — |
Indications
No indication recorded.