drugset

drugset / Trial / NCT02236247

Control of Sinus Node Tachycardia as an Additional Therapy in Patients With Decompensated Heart Failure

NCT02236247 ↗

Phase 1/2 Unknown 50 enrolled University of Sao Paulo Fundação de Amparo à Pesquisa do Estado de São Paulo · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Study aims to compare the I(f) inhibitor ivabradine with placebo as strategy of heart rate control in patients with decompensated heart failure (DHF).

Timeline

Start: 2013-05
Primary completion: 2017-01
Completion: 2017-08

Publications

Results Lofrano-Alves MS, Issa VS, Biselli B, Chizzola P, Ayub-Ferreira SM, Bocchi EA. Control of sinus tachycardia as an additional therapy in patients with decompensated heart failure (CONSTATHE-DHF): A randomized, double-blind, placebo-controlled trial. J Heart Lung Transplant. 2016 Oct;35(10):1260-1264. doi: 10.1016/j.healun.2016.06.005. Epub 2016 Jun 7. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ivabradine	Small molecule	5 mg	Oral

Indications