drugset / Trial / NCT02236403

Treatment of Demodex Blepharitis With Ivermectin Gel 0.1% Plus Metronidazole 1%

NCT02236403

Phase 3 Completed 60 enrolled National University of Colombia
RandomizedParallel-groupDouble-blindTreatment

Summary

Blepharitis is a endemic inflammatory disease caused mainly by Demodex folliculorum and Demodex Brevis, This mites are often associated with anaerobic bacteria that produces a skin inflammation, so a intervention that reduces the number of mites and bacteria would be desirable. Ivermectin a macrolid compound have demonstrated activity against scabies and lice in humans and in animals and a single application have show a good response in lice eradication. In this study , investigators will determinate the security and effectiveness of this compound in the eradication of mites

Timeline

Start
2014-10
Primary completion
2015-01
Completion
2015-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ivermectin Small molecule 0.1 %
Subject Metronidazole Small molecule 1 %

Indications