drugset / Trial / NCT02236403
Treatment of Demodex Blepharitis With Ivermectin Gel 0.1% Plus Metronidazole 1%
RandomizedParallel-groupDouble-blindTreatment
Summary
Blepharitis is a endemic inflammatory disease caused mainly by Demodex folliculorum and Demodex Brevis, This mites are often associated with anaerobic bacteria that produces a skin inflammation, so a intervention that reduces the number of mites and bacteria would be desirable. Ivermectin a macrolid compound have demonstrated activity against scabies and lice in humans and in animals and a single application have show a good response in lice eradication. In this study , investigators will determinate the security and effectiveness of this compound in the eradication of mites
Timeline
- Start
- 2014-10
- Primary completion
- 2015-01
- Completion
- 2015-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ivermectin | Small molecule | 0.1 % | — |
| Subject | Metronidazole | Small molecule | 1 % | — |