drugset / Trial / NCT02237287

Combination of Taliderm® and Vacuum-assisted Closure (VAC) for Treatment of Pressure Ulcers

NCT02237287 ↗

RandomizedFactorialQuadruple-blindTreatment

Summary

Background: The wound healing promoting effect of negative wound pressure therapies (NWPT) takes place at the wound foam interface. Implementation of bioactive substances at this site represents a major research area for the development of future NWPT devices. Methods: Wound healing kinetics of pressure ulcers treated by vacuum assisted closure devices with or without the implementation of a thin interface of poly-N-acetyl glucosamine nanofibers (sNAG) was studied in a prospective randomized clinical trial.

Timeline

Start
2011-02
Primary completion
2012-08
Completion
2012-08

Outcome

Outcome not reported

Stopped: “Open label study part reduced from n=10 to n=6 because of insufficient number of patients under antiaggregation.”

Drugs

EvaluationDrugModalityDoseRoute
Subject poly-N-acetyl glucosamine nanofibers Unknown — —

Indications