drugset / Trial / NCT02238860
A Trial Comparing Entacavir and Tenofovir in Patients With HBV Decompensated Cirrhosis
RandomizedParallel-groupTriple-blindTreatment
Summary
Entacavir and tenofovir are two first line therapies for chronic hepatitis B. Both agents have been claimed equivalent in treatment, there are no head to head trials available in the literature about there effectiveness in HBV Decompensated Cirrhosis. The investigators aimed to compare safety/efficacy and virological response in patients with HBV Decompensated Cirrhosis.
Timeline
- Start
- 2014-09
- Primary completion
- 2016-09
- Completion
- 2016-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Entacavir | Unknown | 0.5 mg | — |
| Comparator | Tenofovir | Small molecule | 300 mg | — |