RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.

Summary

The purpose of this study is to evaluate the safety and immunogenicity of an RSV-F protein nanoparticle vaccine, with aluminum, in healthy third-trimester pregnant women and to assess the impact of maternal immunization on infant safety through one year of life.

Timeline

Start

2014-09

Primary completion

2016-07

Completion

2016-07

Publications

• Munoz FM, Swamy GK, Hickman SP, Agrawal S, Piedra PA, Glenn GM, Patel N, August AM, Cho I, Fries L. Safety and Immunogenicity of a Respiratory Syncytial Virus Fusion (F) Protein Nanoparticle Vaccine in Healthy Third-Trimester Pregnant Women and Their Infants. J Infect Dis. 2019 Oct 22;220(11):1802-1815. doi: 10.1093/infdis/jiz390.

Drugs

Indications