drugset / Trial / NCT02252263

A Phase I Open Label Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma

NCT02252263

Phase 1 Completed 44 enrolled Bristol-Myers Squibb
RandomizedParallel-groupOpen-labelTreatment

Summary

To assess the safety and tolerability, characterize the dose limiting toxicities (DLTs) and identify the maximally tolerated dose (MTD) of Elotuzumab administered in combination with either Lirilumab or Urelumab in subjects with multiple myeloma.

Timeline

Start
2014-12-09
Primary completion
2017-10-10
Completion
2017-10-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Elotuzumab Monoclonal antibody Intravenous
Subject Lirilumab Monoclonal antibody Intravenous
Subject Urelumab Monoclonal antibody Intravenous

Indications