Study to Determine and Compare Plasma and Intrapulmonary Pharmacokinetics of WCK 2349 in Healthy Adult Human Subjects

Phase 1 Completed 30 enrolled Wockhardt Clinartis · collab

NaSingle-groupOpen-labelBasic science

Summary

This study to determine and compare plasma, epithelial lining fluid (ELF) and alveolar macrophage (AM) concentrations of levonadifloxacin after administration of WCK 2349 in healthy adult subjects.

Timeline

Start: 2014-09
Primary completion: 2014-12
Completion: 2015-08

Publications

Rodvold KA, Gotfried MH, Chugh R, Gupta M, Yeole R, Patel A, Bhatia A. Intrapulmonary Pharmacokinetics of Levonadifloxacin following Oral Administration of Alalevonadifloxacin to Healthy Adult Subjects. Antimicrob Agents Chemother. 2018 Feb 23;62(3):e02297-17. doi: 10.1128/AAC.02297-17. Print 2018 Mar.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Alalevonadifloxacin	Small molecule	1000 mg	Oral

Indications

No indication recorded.