drugset / Trial / NCT02258464

Study of Radium-223 Dichloride Versus Placebo and Hormonal Treatment as Background Therapy in Subjects With Bone Predominant HER2 (Human Epidermal Growth Factor Receptor 2) Negative Hormone Receptor Positive Metastatic Breast Cancer

NCT02258464

Phase 2 Terminated 99 enrolled Bayer
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The objective of this study was to assess efficacy and safety of radium-223 dichloride in subjects with human epidermal growth factor receptor 2 negative (HER2 negative) hormone receptor positive breast cancer with bone metastases treated with hormonal treatment background therapy

Timeline

Start
2015-03-02
Primary completion
2019-08-13
Completion
2019-08-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Radium-223 dichloride Other / unclassified 0.05 mbq/kg Intravenous
Subject Radium-223 dichloride Other / unclassified 0.055 mbq/kg Intravenous

Indications