drugset / Trial / NCT02262338
Safety and Dose Ranging Study of Insulin Receptor MoAb-IDS Fusion Protein in Patients With Hunter Syndrome
NaSingle-groupOpen-labelTreatment
Summary
AGT-182 is a fusion protein containing idursulfase that is intended to deliver the enzyme peripherally and to the brain, when administered intravenously. This study is a safety and dose ranging study to obtain safety and exposure data, as well as information on the biological activity of the investigational drug.
Timeline
- Start
- 2015-04
- Primary completion
- 2017-03-27
- Completion
- 2017-03-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AGT-182 | Protein / enzyme biologic | 1 mg/kg | Intravenous |
| Subject | AGT-182 | Protein / enzyme biologic | 3 mg/kg | Intravenous |