drugset / Trial / NCT02262338

Safety and Dose Ranging Study of Insulin Receptor MoAb-IDS Fusion Protein in Patients With Hunter Syndrome

NCT02262338 ↗

Phase 1 Completed 6 enrolled ArmaGen, Inc
NaSingle-groupOpen-labelTreatment

Summary

AGT-182 is a fusion protein containing idursulfase that is intended to deliver the enzyme peripherally and to the brain, when administered intravenously. This study is a safety and dose ranging study to obtain safety and exposure data, as well as information on the biological activity of the investigational drug.

Timeline

Start
2015-04
Primary completion
2017-03-27
Completion
2017-03-27

Drugs

EvaluationDrugModalityDoseRoute
Subject AGT-182 Protein / enzyme biologic 1 mg/kg Intravenous
Subject AGT-182 Protein / enzyme biologic 3 mg/kg Intravenous