drugset / Trial / NCT02268500

VAccination to Improve Clinical outComes in Heart Failure Trial: a Feasibility Study (VACC-HeFT)

NCT02268500

Phase 4 Completed 48 enrolled University of Wisconsin, Madison
RandomizedParallel-groupSingle-blindPrevention

Summary

A multi-center, prospective, randomized, open-label blinded-endpoint trial in patients with heart failure will be conducted; 20 will be assigned to the standard dose vaccine dose and 20 patients to high dose influenza vaccine. Post-vaccine antibody measurements will be assessed, as well as tolerability differences between groups.

Timeline

Start
2014-09
Primary completion
2016-01
Completion
2016-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Influenza Virus Vaccine Vaccine 45 ug Intramuscular
Comparator Influenza Virus Vaccine Vaccine 180 ug Intramuscular

Indications