Effect-site Concentration of Propofol for I-gel Insertion During Anesthesia Induction With a Single-dose Dexmedetomidine

Completed 40 enrolled Gachon University Gil Medical Center

Non-randomizedParallel-groupSingle-blindPrevention

Summary

Before anethetic induction, infuse dexmedetomidine 0.5 mcg/kg for 2 minutes and after injection of lidocaine 30 mg, propofol infusion by using target controlled infusion (TCI) pump. Effect site concentraion of propofol start from 5 and changes the concentration as previous response to i-gel insertion as up and down methods

Timeline

Start: 2014-10
Primary completion: 2015-02
Completion: 2015-02

Publications

Choi JJ, Kim JY, Lee D, Chang YJ, Cho NR, Kwak HJ. Male patients require higher optimal effect-site concentrations of propofol during i-gel insertion with dexmedetomidine 0.5 mug/kg. BMC Anesthesiol. 2016 Mar 22;16:20. doi: 10.1186/s12871-016-0186-1.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Propofol	Small molecule	5 ug/ml	—

Indications

No indication recorded.