drugset / Trial / NCT02269072
Testosterone Regulation of the Natriuretic Peptide System
Withdrawn
Massachusetts General Hospital
RandomizedCrossoverDouble-blindOther
Summary
The proposed study is a physiologic investigation of the effects of testosterone on the natriuretic peptide system. The hypotheses of the study are that testosterone administration will decrease natriuretic peptide levels and salt excretion. The entire protocol is 8 weeks in duration.
Timeline
- Start
- 2015-02
- Primary completion
- 2016-02
- Completion
- 2016-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Testosterone | Small molecule | — | Topical |
| Comparator | Anastrozole | Other / unclassified | — | Oral |
| Comparator | Leuprolide | Other / unclassified | — | — |
| Comparator | Nesiritide | Protein / enzyme biologic | — | Intravenous |