drugset / Trial / NCT02270372
Study of ONT-10 and Varlilumab to Treat Advanced Ovarian or Breast Cancer
NaSingle-groupOpen-labelTreatment
Summary
This is a two-part Phase 1b, open-label study of ONT 10 administered in combination with varlilumab. Two different doses of varlilumab will be studied in combination with the single agent recommended dose of ONT 10. Intermediate and/or lower doses of varlilumab or ONT-10 may also be studied at the recommendation of the safety monitoring committee (SMC).
Timeline
- Start
- 2014-11
- Primary completion
- 2016-06
- Completion
- 2016-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ONT-10 | Vaccine | — | Subcutaneous |
| Subject | Varlilumab | Monoclonal antibody | — | Intravenous |