drugset / Trial / NCT02271945
Safety/Efficacy of MEDI-551 in Combination With Immunomodulating Therapies in Subjects With Aggressive B-cell Lymphomas
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a Phase 1b/2 open-label study to evaluate the safety/efficacy of MEDI-551 + MEDI0680 in participants with relapsed or refractory aggressive B-cell lymphomas who have failed 1-2 prior lines of therapy.
Timeline
- Start
- 2014-12-01
- Primary completion
- 2016-05-24
- Completion
- 2016-05-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Inebilizumab | Monoclonal antibody | 12 mg/kg | Intravenous |
| Subject | MEDI0680 | Monoclonal antibody | 2.5 mg/kg | Intravenous |
| Subject | MEDI0680 | Monoclonal antibody | 10 mg/kg | Intravenous |