drugset / Trial / NCT02271945

Safety/Efficacy of MEDI-551 in Combination With Immunomodulating Therapies in Subjects With Aggressive B-cell Lymphomas

NCT02271945

Phase 1/2 Completed 10 enrolled MedImmune LLC
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a Phase 1b/2 open-label study to evaluate the safety/efficacy of MEDI-551 + MEDI0680 in participants with relapsed or refractory aggressive B-cell lymphomas who have failed 1-2 prior lines of therapy.

Timeline

Start
2014-12-01
Primary completion
2016-05-24
Completion
2016-05-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Inebilizumab Monoclonal antibody 12 mg/kg Intravenous
Subject MEDI0680 Monoclonal antibody 2.5 mg/kg Intravenous
Subject MEDI0680 Monoclonal antibody 10 mg/kg Intravenous