drugset / Trial / NCT02273739

Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation

NCT02273739

Phase 1/2 Completed 21 enrolled Celgene Corporation
NaSequentialOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety, pharmacokinetics, and clinical activity of enasidenib in adults with advanced solid tumors, including glioma, or with angioimmunoblastic T-cell lymphoma (AITL), with an isocitrate dehydrogenase-2 (IDH2) mutation.

Timeline

Start
2014-12-08
Primary completion
2016-06-03
Completion
2016-06-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Enasidenib Small molecule 100 mg Oral
Subject Enasidenib Small molecule 650 mg Oral