drugset / Trial / NCT02275065

Study to Evaluate Safety, Pharmacokinetics, and Antiviral Activity of Bictegravir (GS-9883) in Human Immunodeficiency Virus (HIV)-1 Infected Participants

NCT02275065

Phase 1 Completed 23 enrolled Gilead Sciences
RandomizedSequentialQuadruple-blindTreatment

Summary

The primary objective of the study is to investigate the short-term antiviral potency of bictegravir at multiple doses in antiretroviral (ART) treatment-naive adult participants and participants who are ART-experienced but integrase strand transfer inhibitor (INSTI) naive.

Timeline

Start
2014-10-24
Primary completion
2015-01-23
Completion
2015-01-29

Drugs

EvaluationDrugModalityDoseRoute
Subject bictegravir Small molecule 5 mg Oral
Subject bictegravir Small molecule 25 mg Oral
Subject bictegravir Small molecule 50 mg Oral
Subject bictegravir Small molecule 100 mg Oral