drugset / Trial / NCT02281305

Post-MI PET Scan Imaging of Inflammation

NCT02281305

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Restoring the patency of the coronary vessels and providing the ischemic myocardium with reperfused blood can cause additional tissue damage. A key element of ischemia and reperfusion (I/R) injury and major determinant of the evolution of damage in the affected myocardium is the inflammatory response. The main objective of the study is to evaluate the efficacy of colchicine in reducing I/R injury by effectively modulating the inflammatory response in the reperfused myocardium.

Timeline

Start
2014-10
Primary completion
2015-04
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Colchicine Small molecule 0.5 mg