Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali

Phase 4 Completed 600 enrolled PATH Center for Vaccine Development - Mali · collab University of Maryland · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

This study is an evaluation of the immune response to pentavalent rotavirus vaccine (PRV) after an additional fourth dose is given at 9 months of age with local World Health Organization (WHO) Expanded Programme on Immunization (EPI) vaccines in Mali.

Timeline

Start: 2014-10
Primary completion: 2015-03
Completion: 2015-03

Publications

Haidara FC, Tapia MD, Sow SO, Doumbia M, Coulibaly F, Diallo F, Traore A, Kodio M, Kelly CL, Fitzpatrick M, Kotloff K, Victor JC, Neuzil K. Evaluation of a Booster Dose of Pentavalent Rotavirus Vaccine Coadministered With Measles, Yellow Fever, and Meningitis A Vaccines in 9-Month-Old Malian Infants. J Infect Dis. 2018 Jul 13;218(4):606-613. doi: 10.1093/infdis/jiy215.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Measles vaccine	Vaccine	0.5 ml	Subcutaneous
Subject	Rotarix	Vaccine	2 ml	Oral
Subject	Yellow Fever Vaccine	Vaccine	0.5 ml	Intramuscular
Subject	meningitis conjugate vaccine	Vaccine	0.5 ml	Intramuscular

Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali

Summary

Timeline

Publications

Drugs

Indications