drugset / Trial / NCT02295124
Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement Surgery
RandomizedParallel-groupDouble-blindTreatment
Summary
The study aims to compare the incidence of side effects caused by Oxycodone and Hydromorphone.
Timeline
- Start
- 2012-08
- Primary completion
- 2016-01
- Completion
- 2016-01
Publications
- Background Macario A, Weinger M, Carney S, Kim A. Which clinical anesthesia outcomes are important to avoid? The perspective of patients. Anesth Analg. 1999 Sep;89(3):652-8. doi: 10.1097/00000539-199909000-00022.
- Background Pavlin DJ, Rapp SE, Polissar NL, Malmgren JA, Koerschgen M, Keyes H. Factors affecting discharge time in adult outpatients. Anesth Analg. 1998 Oct;87(4):816-26. doi: 10.1097/00000539-199810000-00014.
- Background Hartrick C, Van Hove I, Stegmann JU, Oh C, Upmalis D. Efficacy and tolerability of tapentadol immediate release and oxycodone HCl immediate release in patients awaiting primary joint replacement surgery for end-stage joint disease: a 10-day, phase III, randomized, double-blind, active- and placebo-controlled study. Clin Ther. 2009 Feb;31(2):260-71. doi: 10.1016/j.clinthera.2009.02.009.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hydromorphone | Other / unclassified | 1 mg | — |
| Comparator | Hydromorphone | Other / unclassified | 2 mg | — |
| Comparator | Oxycodone | Other / unclassified | 5 mg | — |
| Comparator | Oxycodone | Other / unclassified | 10 mg | — |
Indications
No indication recorded.