drugset
drugset / Trial / NCT02295553

Ketamine and Propofol for Upper Endoscopy

NCT02295553 ↗

Phase 4 Completed 56 enrolled The Hospital for Sick Children
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to examine the dose-response relationship of ketamine in combination with propofol.

Timeline

Start
2013-07
Primary completion
2016-12
Completion
2016-12

Outcome

Met primary endpoint

paper the ketamine 1 mg kg-1 group (6.1, 4.1-8.1; 4.5, 2.9-6; 4.7, 3.1-6.2 mg kg-1vs 1.1, 0.5-1.8 mg kg-1, respectively, P<0.008). PMID 30032885 ↗

Publications

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.25 mg/kg Intravenous
Subject Ketamine Small molecule 0.5 mg/kg Intravenous
Subject Ketamine Small molecule 1 mg/kg Intravenous
Subject Propofol Small molecule 2 mg/kg Intravenous
Subject Propofol Small molecule 2.5 mg/kg Intravenous
Subject Propofol Small molecule 3 mg/kg Intravenous
Subject Propofol Small molecule 4 mg/kg Intravenous

Indications

No indication recorded.