drugset / Trial / NCT02297412

Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel

NCT02297412

RandomizedParallel-groupDouble-blindSupportive care

Summary

This randomized pilot trial studies how well minocycline hydrochloride works in reducing chemotherapy-induced peripheral neuropathy and acute pain in patients with breast cancer undergoing treatment with paclitaxel. Drugs used in chemotherapy, such as paclitaxel, may cause damage to nerves that result in aches, pains, and tingling or numbness of fingers and toes. Minocycline hydrochloride may help lessen nerve damage from paclitaxel and improve the quality of life in breast cancer patients.

Timeline

Start
2014-11
Primary completion
2016-07-08
Completion
2016-07-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Minocycline Small molecule Oral