drugset / Trial / NCT02300350

DDI Study With Multiple-dose LX4211 and Single Dose Digoxin

NCT02300350

Phase 1 Completed 24 enrolled Lexicon Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study will be conducted as a single-center, open-label, 2-period, single-sequence, drug-drug interaction study to assess the effects of multiple dose LX4211 (400 mg administered as 2 × 200-mg tablets qd × 12 days) on the PK of single-dose digoxin (2 × 0.25-mg tablets) in healthy male and female subjects.

Timeline

Start
2014-10
Primary completion
2014-12
Completion
2014-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Digoxin Other / unclassified 0.5 mg Oral
Subject Sotagliflozin Small molecule 400 mg Oral

Indications

No indication recorded.