Effects of Sitaglpitin on Endothelial Function During the OGTT in T2DM

Summary

To investigate whether single administration of sitaglitpin can restore acute endothelial dysfunction and ameliorate impaired increase of the number of endothelial progenitor cells (EPCs) after oral glucose loading in patients with T2DM. To compare the effect of sitagliptin and glimepiride on endothelial function evaluated by flow-mediated vasodilatation (FMD) and the number of circulating EPCs in patients with T2DM.

Timeline

Start

2015-01

Primary completion

2017-06

Completion

2017-07

Drugs

Indications