drugset / Trial / NCT02303496

Autologous Platelet-Rich Plasma Cream for Photoaging and Chronological Skin Aging

NCT02303496

Phase 1/2 Unknown 20 enrolled Acibadem University
RandomizedSingle-groupDouble-blindTreatment

Summary

Human skin undergoes some morphological changes with the effects of chronological aging and photoaging, these are especially remarkable in the facial skin. Changes in pigmentation, sallowness, deep wrinkling, laxity and elastosis are the main changes seen in photoaging and chronologic aging of skin. With the increasing demand, it needs to provide new approach for the prevention and treatment of these morphological changes. Fibroblasts have a key role on skin aging. It is known that platelet rich plasma activates the fibroblasts and increases the synthesis of collagen and other type of matrix components. Because of these specialities, platelet rich plasma is thought to be effective on skin aging.

Timeline

Start
2014-12
Primary completion
2015-03
Completion
2015-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Platelet Rich Plasma Other / unclassified Topical

Indications