drugset / Trial / NCT02303912

Safety and Efficacy Study of Nuc-1031 and Carboplatin Combination to Treat Recurrent Ovarian Cancer

NCT02303912

Phase 1 Completed 25 enrolled Imperial College Healthcare NHS Trust
NaSingle-groupOpen-labelTreatment

Summary

A first in human experimental treatment in which an experimental medicine,Nuc-1031, is used in combination with a standard cancer medicine, carboplatin, to treat ovarian cancer which reappear after standard cancer treatment. The aim of the trial is to determine safety, effectiveness, and clinical activity of this combination treatment.

Timeline

Start
2014-11
Primary completion
2017-01-23
Completion
2017-01-23

Drugs

EvaluationDrugModalityDoseRoute
Subject FOSGEMCITABINE PALABENAMIDE Small molecule Intravenous
Background Carboplatin Small molecule Intravenous

Indications