drugset / Trial / NCT02321319

Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients

NCT02321319

Phase 3 Terminated 5 enrolled Mallinckrodt
NaSingle-groupOpen-labelTreatment

Summary

This pediatric study is designed to provide safety information, dosing guidelines, and a pharmacokinetic (PK) evaluation of once-daily hydromorphone hydrochloride (HCl) extended-release (ER) tablets in children with chronic painful conditions who are "opioid-tolerant" prior to enrollment under the Pediatric Research Equity Act (PREA) of 2003.

Timeline

Start
2017-03-11
Primary completion
2019-02-04
Completion
2019-02-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydromorphone Other / unclassified 4 mg
Subject Hydromorphone Other / unclassified 16 mg

Indications