drugset / Trial / NCT02323529
Efficacy and Safety of Once Daily Dosing Compared to Twice Daily Dosing of Nitisinone in HT-1
CrossoverOpen-labelTreatment
Summary
The purpose of this study is to look at the steady-state serum concentrations of nitisinone when switching from twice daily and once daily dosing.
Timeline
- Start
- 2014-12
- Primary completion
- 2015-09
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nitisinone | Small molecule | 1 mg/kg | — |
| Subject | Nitisinone | Small molecule | 2 mg/kg | — |