drugset / Trial / NCT02328144

Effectiveness of Metronidazole in Pain Control Posthemorrhoidectomy

NCT02328144

Phase 3 Completed 44 enrolled Mexican Social Security Institute
RandomizedParallel-groupDouble-blindTreatment

Summary

Hemorrhoidal disease occurs in 50% of people over 40 years old and is the most common cause of anorectal surgery. One of the complications of hemorrhoidectomy is pain, which is a difficult symptom to appreciate and assess, by its frequent and large variations in sensitivity in each patient. Many studies have been done to reduce patient postoperative pain, but there is no ideal method. The application of both oral and topical metronidazole has shown to decrease pain following hemorrhoidectomy, but its use is not standardized. The investigators evaluated the effect of oral administration of metronidazole versus homologated placebo in pain control after hemorrhoidectomy

Timeline

Start
2013-07
Primary completion
2014-08
Completion
2014-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metronidazole Small molecule 500 mg Oral

Indications