drugset / Trial / NCT02329184

Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-461

NCT02329184

Phase 1 Completed 15 enrolled MyoKardia, Inc.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to establish initial safety, tolerability, pharmacokinetics and pharmacodynamics of MYK-461 in human subjects. This is a sequential group, single ascending (oral) dose study in NYHA Class I, II, or III patient volunteers aged 18-65 years.

Timeline

Start
2014-12
Primary completion
2016-03
Completion
2016-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Mavacamten Small molecule Oral