drugset / Trial / NCT02330991
A Trial of One-week on/One-week Off Temozolomide Versus Continuous Dose-Intense Temozolomide in Patients With Glioblastoma Multiforme at First Relapse
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the clinical benefit and safety of two different Dose-Intense temozolomide regimens（one-week on/one-week off regimen versus continuous dose-intense regimen）in patients with glioblastoma at first relapse.
Timeline
- Start
- 2015-01
- Primary completion
- 2020-03
- Completion
- 2020-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Temozolomide | Small molecule | 50 mg/m2 | — |
| Subject | Temozolomide | Small molecule | 150 mg/m2 | — |