drugset / Trial / NCT02331693

CAR T Cells in Treating Patients With Malignant Gliomas Overexpressing EGFR

NCT02331693 ↗

Phase 1 Unknown 10 enrolled RenJi Hospital
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether autologous T cells bearing chimeric antigen receptor that can specifically recognize EGFR overexpressed in tumor cells is safe and effective for patients with EGFR-overexpressing malignant glioma.

Timeline

Start
2014-12
Primary completion
2015-12
Completion
2016-12

Drugs

EvaluationDrugModalityDoseRoute
Subject anti-EGFR CAR T Cell therapy — Intravenous

Indications