To Study the Effect of Adjunctive Oral Methylprednisolone Therapy in Pediatric Urinary Tract Infection

Summary

Purposes of this study will be as follows: 1. To design a prospective, randomized, and open-labeled study to investigate the effect and the side effect of MPD in combination with conventional antibiotics to affect clinical course, outcome, and medical expenses. 2. To compare level of the urinary and serum cytokines before and after received MPD for the following sub-aim: I. To determine the population who is benefit from MPD to reduce the severity of clinical course and subsequent renal scarring. II. To understand the mechanism by which the MPD could shorten the clinical course and reduce the renal scarring.

Timeline

Start

2015-01

Primary completion

2015-12

Completion

2015-12

Drugs

Indications