drugset / Trial / NCT02333045
Characterization and Modulation of Mucosal Immunity for HIV Prevention in Women
RandomizedParallel-groupOpen-labelPrevention
Summary
This study seeks to understand the immune cells in the cervical fluid of in the blood and genital tract of HIV-negative healthy female volunteers and to see if these cells can be modified using a combined anti-viral and antiinflammatory drug called maraviroc, a medicine used in the treatment of HIV infection.
Timeline
- Start
- 2015-01
- Primary completion
- 2016-10-28
- Completion
- 2016-10-28
Outcome
Outcome not reported
Stopped: “Minimal efficacy of maraviroc alone was found in preliminary data analysis of another study.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Maraviroc | Other / unclassified | 300 mg | Oral |
| Subject | Truvada | Unknown | 1 unknown | Oral |