drugset / Trial / NCT02334163
The Effects of Nitazoxanide in Hepatic Encephalopathy
RandomizedParallel-groupOpen-labelTreatment
Summary
Evaluating the efficacy and safety of nitazoxanide in comparison to standard treatment in patients with grade II-III hepatic encephalopathy (HE). Also, Evaluating the effect of administering nitazoxanide on the improvement of patient's quality of life.
Timeline
- Start
- 2014-12
- Primary completion
- 2015-02
- Completion
- 2015-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metronidazole | Small molecule | 250 mg | — |
| Subject | Nitazoxanide | Other / unclassified | 500 mg | — |
| Comparator | rifaximine | Unknown | 400 mg | — |
| Background | Lactulose | Other / unclassified | — | Oral |