drugset / Trial / NCT02334501
Open-label PK Study to Evaluate Lansoprazole and Neratinib in Healthy Subjects
NaSingle-groupOpen-label
Summary
This is an open label, 2-period, fixed-sequence study in 15 healthy adult subjects under fed conditions. To evaluate the effect of multiple doses of lansoprazole on the absorption and pharmacokinetics (PK) of a single dose of neratinib in healthy subjects.
Timeline
- Start
- 2014-08
- Primary completion
- 2014-10
- Completion
- 2014-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lansoprazole | Other / unclassified | 30 mg | Oral |
| Subject | Neratinib | Small molecule | 240 mg | Oral |
Indications
No indication recorded.