High Volume Simethicone VCE Clinical Trial

Summary

Video capsule endoscopy (VCE) is a procedure where a small camera is swallowed to examine the small bowel. Although the procedure is useful for diagnosing small bowel diseases, air bubbles can obscure the recorded images. Simethicone is a medication that can be used to disperse the air bubbles. However, prior studies using this medication have shown only a modest benefit. In our study, we would like to investigate whether increasing the amount of medication will improve the recorded images further.

Timeline

Start

2017-01

Primary completion

2019-08

Completion

2019-10

Publications

• Sey M, Yan B, McDonald C, Segal D, Friedland J, Puka K, Jairath V. A randomized controlled trial of high volume simethicone to improve visualization during capsule endoscopy. PLoS One. 2021 Apr 1;16(4):e0249490. doi: 10.1371/journal.pone.0249490. eCollection 2021.

Drugs

Indications